Abstract
Congenital pulmonary hypoplasia is a devastating condition affecting fetal and newborn pulmonary physiology, resulting in great morbidity and mortality. The fetal lung develops in a fluid-filled environment. In this paper, we describe a novel, implantable pressure sensing and recording device which we use to study the pressures present in the fetal pulmonary tree throughout gestation. The system achieves 0.18 cm H2O resolution and can record for 21days continuously at 256Hz. Sample tracings of in vivo fetal lamb recordings are shown.
Original language | English (US) |
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Article number | 6236172 |
Pages (from-to) | 1208-1215 |
Number of pages | 8 |
Journal | IEEE Transactions on Information Technology in Biomedicine |
Volume | 16 |
Issue number | 6 |
DOIs | |
State | Published - 2012 |
Funding
Manuscript received February 4, 2012; revised May 5, 2012; accepted June 27, 2012. Date of publication July 10, 2012; date of current version November 16, 2012. This work was supported by National Institutes of Health (NIH) Small Business Innovation Research under Grant 1R41HL110466-01, and the Food and Drug Administration through the Pediatric Device Consortium under Grant 2P50FD003793-03. The work of M. Etemadi was supported by the Medical Scientist Training Program grant through the National Institutes of Health. The work of S. C. Schecter was supported by the NIH T32 Training Grant GM008258-23.
Keywords
- Data logger
- fetal surgery
- ultralow pressure sensing
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Biotechnology
- Computer Science Applications