Implementing large-scale ENU mutagenesis screens in North America

Amander T. Clark, Daniel Goldowitz, Joseph S. Takahashi, Martha Hotz Vitaterna, Sandra M. Siepka, Luanne L. Peters, Wayne N. Frankel, George A. Carlson, Janet Rossant, Joseph H. Nadeau, Monica J. Justice

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.

Original languageEnglish (US)
Pages (from-to)51-64
Number of pages14
Issue number1
StatePublished - Sep 2004


  • Human Genome Project
  • Mouse Genome Project
  • balancer chromosomes
  • mouse mutagenesis
  • phenotype screens

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Genetics
  • Plant Science
  • Insect Science


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