Implementing Preoperative Penicillin Allergy Testing in Surgical Patients

Ravindra Alok Gupta, Howard Lee, Obianuju Okocha*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Penicillin allergy is the most reported immunoglobulin E (IgE)-mediated reaction. About 10% of the general population and 20% of hospitalized patients have a history of penicillin allergy. Unconfirmed penicillin allergy with subsequent administration of second-line antibiotics has been associated with increased morbidity. However, when penicillin allergy testing is performed, the incidence of IgE-mediated reactions is extremely low; in fact, the negative predictive value of penicillin allergy testing exceeds 99%. This article aims to briefly describe implementing safe penicillin allergy testing as a routine test during the preoperative evaluation of surgical patients.

Original languageEnglish (US)
Pages (from-to)E01659
JournalA&A practice
Issue number2
StatePublished - Feb 3 2023

ASJC Scopus subject areas

  • Medicine(all)


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