Implicit perceptual-motor skill learning in mild cognitive impairment and parkinson's disease

Eric W. Gobel, Kelsey Blomeke, Cindy Zadikoff, Tanya Simuni, Sandra Weintraub, Paul J. Reber*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


Objective: Implicit skill learning is hypothesized to depend on nondeclarative memory that operates independent of the medial temporal lobe (MTL) memory system and instead depends on cortico striatal circuits between the basal ganglia and cortical areas supporting motor function and planning. Research with the Serial Reaction Time (SRT) task suggests that patients with memory disorders due to MTL damage exhibit normal implicit sequence learning. However, reports of intact learning rely on observations of no group differences, leading to speculation as to whether implicit sequence learning is fully intact in these patients. Patients with Parkinson's disease (PD) often exhibit impaired sequence learning, but this impairment is not universally observed.

Original languageEnglish (US)
Pages (from-to)314-321
Number of pages8
Issue number3
StatePublished - 2013


  • Implicit memory
  • Mild cognitive impairment
  • Parkinson's disease
  • Sequence learning
  • Skill learning

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology


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