Improved synthesis of 1,5-dinaphtho[38]crown-10

Carson J. Bruns, Subhadeep Basu, J. Fraser Stoddart*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


We have devised a method of achieving the much-used macrocyclic polyether, 1,5-dinaphtho[38]crown-10, in three steps by a route that is more efficient and requires fewer purification procedures than those reported in the literature to date. The strategy can also be extended to the synthesis of asymmetric crown-10 ether derivatives with one 1,5-dinaphtho ring system.

Original languageEnglish (US)
Pages (from-to)983-986
Number of pages4
JournalTetrahedron Letters
Issue number6
StatePublished - Feb 10 2010


  • Crown ethers
  • Macrocyclic polyethers
  • Mechanically interlocked molecules
  • Templates

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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