Improving Geographic Equity in Kidney Transplantation Using Alternative Kidney Sharing and Optimization Modeling

Ashley E. Davis, Sanjay Mehrotra*, John J. Friedewald, Mark S. Daskin, Anton I. Skaro, Michael M. Abecassis, Daniela P. Ladner

*Corresponding author for this work

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The national demand for kidney transplantation far outweighs the supply of kidney organs. Currently, a patient's ability to receive a kidney transplant varies depending on where he or she seeks transplantation. This reality is in direct conflict with a federal mandate from the Department of Health and Human Services. We analyze current kidney allocation and develop an alternative kidney sharing strategy using a multiperiod linear optimization model, KSHARE. KSHARE aims to improve geographic equity in kidney transplantation while also respecting transplant system constraints and priorities. KSHARE is tested against actual 2000-2009 kidney allocation using Organ Procurement and Transplant Network data. Geographic equity is represented by minimizing the range in kidney transplant rates around local areas of the country. In 2009, less than 25% of standard criteria donor kidneys were allocated beyond the local area of procurement, and Donor Service Area kidney transplantation rates varied from 3.0% to 30.0%, for an overall range of 27.0%. Given optimal sharing of kidneys within 600 miles of procurement for 2000-2009, kidney transplant rates vary from 5.0% to 12.5% around the country for an overall kidney transplant range of 7.5%. Nationally sharing kidneys optimally between local areas only further decreases the transplant rate range by 1.7%. Enhancing the practice of sharing kidneys by the KSHARE model may increase geographic equity in kidney transplantation.

Original languageEnglish (US)
Pages (from-to)797-807
Number of pages11
JournalMedical Decision Making
Volume35
Issue number6
DOIs
StatePublished - Aug 10 2015

Keywords

  • equity
  • geography
  • optimization
  • organ allocation

ASJC Scopus subject areas

  • Health Policy

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