Improving the reliability of the auditory middle latency response by monitoring EEG delta activity

Therese McGee*, Nina Kraus, Mead Killion, Richard Rosenberg, Cynthia King

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


The auditory middle latency response (MLR), a useful tool in the assessment of low frequency auditory sensitivity, can be consistently recorded in young children during wakefulness, stages 1 and 2, and REM sleep. Responses are often absent or questionable during stage 4. An on-line measure indicating favorable periods for recording MLR during sleep is important for interpretation of absent potentials. Here, for children 5 to 7 years old, the reliability and detectability of MLR was compared to sleep state and the dominance of delta activity (0-3 Hz) in the EEG frequency spectrum. Dominance of delta activity, a characteristic of stage 4, was expressed in a “delta ratio,” a measure of relative EEG energy in the 0 to 3 Hz frequency spectrum. A fixed delta ratio (DR=9) allowed the differentiation of periods favorable for MLR. MLR wave Pa amplitude and latency also varied with delta ratio. Results indicate that on-line monitoring of the delta ratio will allow reliable testing of MLR in clinical situations.

Original languageEnglish (US)
Pages (from-to)76-84
Number of pages9
JournalEar and hearing
Issue number2
StatePublished - Apr 1993

ASJC Scopus subject areas

  • Speech and Hearing
  • Otorhinolaryngology


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