In a wild germinal center, what determines survival of the fittest?

Emily M. Flowers; Stephanie C. Eisenbarth

doi:10.1126/sciimmunol.adn7535

In a wild germinal center, what determines survival of the fittest?

Emily M. Flowers, Stephanie C. Eisenbarth

Medicine, Allergy Division

Research output: Contribution to journal › Article › peer-review

Abstract

Mice with natural BCR frequencies have plasma cells enriched for high-affinity clones, but high-affinity clones persist in the germinal center, leaving the rules for plasma cell selection still murky.

Original language	English (US)
Pages (from-to)	eadn7535
Journal	Science Immunology
Volume	9
Issue number	91
DOIs	https://doi.org/10.1126/sciimmunol.adn7535
State	Published - Jan 5 2024

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1126/sciimmunol.adn7535

Cite this

@article{b23d17e6cad44c11b472f92b394267b0,

title = "In a wild germinal center, what determines survival of the fittest?",

abstract = "Mice with natural BCR frequencies have plasma cells enriched for high-affinity clones, but high-affinity clones persist in the germinal center, leaving the rules for plasma cell selection still murky.",

author = "Flowers, {Emily M.} and Eisenbarth, {Stephanie C.}",

year = "2024",

month = jan,

day = "5",

doi = "10.1126/sciimmunol.adn7535",

language = "English (US)",

volume = "9",

pages = "eadn7535",

journal = "Science Immunology",

issn = "2470-9468",