In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

Jonathan J. Cherry, Christine J. Didonato*, Elliot J. Androphy, Alessandro Calo, Kyle Potter, Sara K. Custer, Sarah Du, Timothy L. Foley, Ariamala Gopalsamy, Emily J. Reedich, Susana M. Gordo, William Gordon, Natalie Hosea, Lyn H. Jones, Daniel K. Krizay, Gregory Larosa, Hongxia Li, Sachin Mathur, Carol A. Menard, Paraj PatelRebeca Ramos-Zayas, Anne Rietz, Haojing Rong, Baohong Zhang, Michael A. Tones

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science