TY - JOUR
T1 - In vitro effect of cystographic contrast media on urinary tract pathogens
AU - Kuhns, Lawrence R.
AU - Baublis, Joseph V.
AU - Grecory, Janet
AU - Poznanski, Andrew K.
PY - 1972/1/1
Y1 - 1972/1/1
N2 - Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.
AB - Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.
KW - Cystourethrography
KW - Iodine-containing compounds
KW - Urinary infection
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U2 - 10.1097/00004424-197203000-00008
DO - 10.1097/00004424-197203000-00008
M3 - Article
C2 - 4554443
AN - SCOPUS:0015313246
SN - 0020-9996
VL - 7
SP - 112
EP - 117
JO - Investigative Radiology
JF - Investigative Radiology
IS - 2
ER -