In vitro effect of cystographic contrast media on urinary tract pathogens

Lawrence R. Kuhns*, Joseph V. Baublis, Janet Grecory, Andrew K. Poznanski

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.

Original languageEnglish (US)
Pages (from-to)112-117
Number of pages6
JournalInvestigative Radiology
Issue number2
StatePublished - Jan 1 1972


  • Cystourethrography
  • Iodine-containing compounds
  • Urinary infection

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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