In vitro effect of cystographic contrast media on urinary tract pathogens

Lawrence R. Kuhns; Joseph V. Baublis; Janet Grecory; Andrew K. Poznanski

doi:10.1097/00004424-197203000-00008

In vitro effect of cystographic contrast media on urinary tract pathogens

Lawrence R. Kuhns^*, Joseph V. Baublis, Janet Grecory, Andrew K. Poznanski

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.

Original language	English (US)
Pages (from-to)	112-117
Number of pages	6
Journal	Investigative Radiology
Volume	7
Issue number	2
DOIs	https://doi.org/10.1097/00004424-197203000-00008
State	Published - Jan 1 1972

Keywords

Cystourethrography
Iodine-containing compounds
Urinary infection

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/00004424-197203000-00008

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title = "In vitro effect of cystographic contrast media on urinary tract pathogens",

abstract = "Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.",

keywords = "Cystourethrography, Iodine-containing compounds, Urinary infection",

author = "Kuhns, {Lawrence R.} and Baublis, {Joseph V.} and Janet Grecory and Poznanski, {Andrew K.}",

year = "1972",

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doi = "10.1097/00004424-197203000-00008",

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T1 - In vitro effect of cystographic contrast media on urinary tract pathogens

AU - Kuhns, Lawrence R.

AU - Baublis, Joseph V.

AU - Grecory, Janet

AU - Poznanski, Andrew K.

PY - 1972/1/1

Y1 - 1972/1/1

N2 - Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.

AB - Sodium acetrizoate 24% was found in vitro to be bacteriocidal to live strains each of Escherichia coli, Proteus, Klebsiella, and Pseudomonas which were isolated from children with urinary tract infections; 25% sodium diatrizoate was bacteriostatic to these same strains in vitro, except for the E. coli strains, for which it was bacteriocidal. The theoretical implications of these findings, if applicable to clinical situations, are that sodium acetrizoate would be the contrast medium of choice for cystourethrography in a patient with retained urine after the procedure (e.g., in neurogenic bladder), while sodium diatrizoate would be the agent of choice if the possibility for soft tissue extravasation exists.

KW - Cystourethrography

KW - Iodine-containing compounds

KW - Urinary infection

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In vitro effect of cystographic contrast media on urinary tract pathogens

Abstract

Keywords

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