In vitro synthesis and stabilization of amorphous calcium carbonate (ACC) nanoparticles within liposomes

Chantel C. Tester; Ryan E. Brock; Ching Hsuan Wu; Minna R. Krejci; Steven Weigand; Derk Joester

doi:10.1039/c1ce05153a

In vitro synthesis and stabilization of amorphous calcium carbonate (ACC) nanoparticles within liposomes

Chantel C. Tester, Ryan E. Brock, Ching Hsuan Wu, Minna R. Krejci, Steven Weigand, Derk Joester^*

^*Corresponding author for this work

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

We show that amorphous calcium carbonate (ACC) can be synthesized in phospholipid bilayer vesicles (liposomes). Liposome-encapsulated ACC nanoparticles are stable against aggregation, do not crystallize for at least 20 h, and are ideally suited to investigate the influence of lipid chemistry, particle size, and soluble additives on ACC in situ.

Original language	English (US)
Pages (from-to)	3975-3978
Number of pages	4
Journal	CrystEngComm
Volume	13
Issue number	12
DOIs	https://doi.org/10.1039/c1ce05153a
State	Published - Jun 21 2011

ASJC Scopus subject areas

Chemistry(all)
Materials Science(all)
Condensed Matter Physics

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abstract = "We show that amorphous calcium carbonate (ACC) can be synthesized in phospholipid bilayer vesicles (liposomes). Liposome-encapsulated ACC nanoparticles are stable against aggregation, do not crystallize for at least 20 h, and are ideally suited to investigate the influence of lipid chemistry, particle size, and soluble additives on ACC in situ.",

author = "Tester, {Chantel C.} and Brock, {Ryan E.} and Wu, {Ching Hsuan} and Krejci, {Minna R.} and Steven Weigand and Derk Joester",

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AU - Tester, Chantel C.

AU - Brock, Ryan E.

AU - Wu, Ching Hsuan

AU - Krejci, Minna R.

AU - Weigand, Steven

AU - Joester, Derk

PY - 2011/6/21

Y1 - 2011/6/21

N2 - We show that amorphous calcium carbonate (ACC) can be synthesized in phospholipid bilayer vesicles (liposomes). Liposome-encapsulated ACC nanoparticles are stable against aggregation, do not crystallize for at least 20 h, and are ideally suited to investigate the influence of lipid chemistry, particle size, and soluble additives on ACC in situ.

AB - We show that amorphous calcium carbonate (ACC) can be synthesized in phospholipid bilayer vesicles (liposomes). Liposome-encapsulated ACC nanoparticles are stable against aggregation, do not crystallize for at least 20 h, and are ideally suited to investigate the influence of lipid chemistry, particle size, and soluble additives on ACC in situ.

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In vitro synthesis and stabilization of amorphous calcium carbonate (ACC) nanoparticles within liposomes

Abstract

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