In vitro synthesis and stabilization of amorphous calcium carbonate (ACC) nanoparticles within liposomes

Chantel C. Tester, Ryan E. Brock, Ching Hsuan Wu, Minna R. Krejci, Steven Weigand, Derk Joester*

*Corresponding author for this work

Research output: Contribution to journalArticle

57 Scopus citations


We show that amorphous calcium carbonate (ACC) can be synthesized in phospholipid bilayer vesicles (liposomes). Liposome-encapsulated ACC nanoparticles are stable against aggregation, do not crystallize for at least 20 h, and are ideally suited to investigate the influence of lipid chemistry, particle size, and soluble additives on ACC in situ.

Original languageEnglish (US)
Pages (from-to)3975-3978
Number of pages4
Issue number12
StatePublished - Jun 21 2011


ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

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