In vivo metabolism and final disposition of a novel nonsteroidal androgen in rats and dogs

Keyphrases

• Androgens 100%
• Oral Bioavailability 100%
• Non-steroidal 100%
• In Vitro Metabolism 100%
• Final Disposition 100%
• Metabolism 66%
• Metabolic Pathway 66%
• Nitro Group 66%
• A-ring 66%
• Pharmacokinetics 33%
• Testosterone 33%
• Prostate 33%
• Pharmacologic 33%
• Pharmacokinetic Properties 33%
• Hydrolysis 33%
• Deacetylation 33%
• Amide Bond 33%
• Androgen Receptor 33%
• Methyl 33%
• Dose Effect 33%
• Species Differences 33%
• Hepatic Metabolism 33%
• Receptor Binding Affinity 33%
• Nitro 33%
• Trifluoromethyl 33%
• Phenoxy 33%
• Acetamide 33%
• Phase II Metabolites 33%
• Pharmacologic Effects 33%
• Phase II Enzymes 33%
• Linear Pharmacokinetics 33%
• Linear Kinetics 33%
• Selective Androgen Receptor Modulator 33%
• Amide Reduction 33%
• Phenylpropionamides 33%
• Androgen Agonist 33%
• Oxidative Metabolites 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Androgen 100%
• Bioavailability 100%
• Pharmacokinetics 100%
• Acetamide 33%
• Androgen Receptor 33%
• Selective Androgen Receptor Modulator 33%
• Carboxamide 33%