In vivo severity ranking of Ras pathway mutations associated with developmental disorders

Keyphrases

• Developmental Disorders 100%
• Severity Ranking 100%
• RASopathies 100%
• Pathway mutation 100%
• In Cancer 25%
• Patient-specific 25%
• Disease Progression 25%
• Genome Sequencing 25%
• Drosophilidae 25%
• Intrinsic Properties 25%
• Disease-causing mutations 25%
• Drug Dosing 25%
• Zebrafish 25%
• Germline mutation 25%
• Disease Prediction 25%
• Mutational Effects 25%
• MEK1 25%
• Multiple Diseases 25%
• Human Birth 25%
• Systematic Framework 25%
• Patient-specific Predictions 25%
• Zebrafish Embryo 25%
• RAS-MAPK Pathway 25%
• Robust Rank Aggregation 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Zebra Fish 100%
• Malignant Neoplasm 100%
• Developmental Disorder 100%
• Drug Dose 50%
• Phosphotransferase 50%
• Disease Exacerbation 50%
• Comorbidity 50%

Biochemistry, Genetics and Molecular Biology

• Zebra Fish 100%
• Genome Sequencing 50%
• Translating (Language) 50%
• Germline Mutation 50%
• Drug Dose 50%
• Kinase 50%
• Phosphotransferase 50%
• Mitogen-Activated Protein Kinase 50%
• Comorbidity 50%