@inproceedings{c990891cc7874ea49b764a32cd65de72,
title = "In vivo two-photon imaging measuring the blood-brain barrier permeability during early postnatal brain development in rodent",
abstract = "The blood-brain barrier (BBB) is a unique structure between the cerebral blood circulation and the delicate neural environment that is important in regulating the movement of molecules and ions involved in brain development and function. However, little is known about the physiological permeability of molecules and ions across the BBB during brain development. In this study we applied an innovative approach to examine the development of BBB properties quantitatively. Two-photon microscopy was employed to measure BBB permeability in real time in vivo. Vascular growth and specific interactions between astrocyte end feet and microvessels were studied by using a combination of IB4 histochemistry, immunohistochemistry, confocal microscopy and 3D analysis.",
keywords = "Two-Photon imaging, astrocytes, blood-brain barrier, cerebral microvessel, immunohistochemistry, permeability, postnatal brain development",
author = "Lingyan Shi and Adri{\'a}n Rodr{\'i}guez-Contreras",
note = "Publisher Copyright: Copyright {\textcopyright} 2016 SPIE.; Multiphoton Microscopy in the Biomedical Sciences XVI ; Conference date: 14-02-2016 Through 16-02-2016",
year = "2016",
doi = "10.1117/12.2219571",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "So, {Peter T. C.} and Karsten Konig and Ammasi Periasamy and Karsten Konig",
booktitle = "Multiphoton Microscopy in the Biomedical Sciences XVI",
}