Incidence and Clinical Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 Infection After Vaccination in Children

Megan E. Reyna, Priya R. Edward, Egon A. Ozer, Lacy M. Simons, Judd F. Hultquist, Ramon Lorenzo-Redondo, Ami B. Patel, Larry K. Kociolek*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of this single-center cohort study was to characterize the frequency, clinical characteristics, and molecular epidemiology of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after vaccination. Between May 15, 2021, and January 1, 2022, 171 children experienced SARS-CoV-2 infection postvaccination, 146 (86%) following the Omicron variant predominance. Outcomes were generally mild and comparable before and after Omicron predominance.

Original languageEnglish (US)
Pages (from-to)196-201.e4
Journaljournal of pediatrics
Volume251
DOIs
StatePublished - Dec 2022

Keywords

  • COVID-19
  • SARS-CoV-2
  • breakthrough
  • pediatric
  • vaccine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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