Incidence of seizures in patients with multiple sclerosis treated with intrathecal baclofen

S. U. Schuele*, C. Kellinghaus, S. J. Shook, N. Boulis, F. A. Bethoux, T. Loddenkemper

*Corresponding author for this work

Research output: Contribution to journalArticle

51 Scopus citations

Abstract

Oral and intrathecal baclofen (ITB) have been associated with epileptic seizures. The authors observed a higher incidence of epileptic seizures in 99 patients with multiple sclerosis (MS) treated with ITB vs a matched control group (7% vs 1%, p < 0.05). Three patients with MS on ITB developed status epilepticus. Seizures were often associated with additional triggering factors.

Original languageEnglish (US)
Pages (from-to)1086-1087
Number of pages2
JournalNeurology
Volume64
Issue number6
DOIs
StatePublished - Mar 22 2005

ASJC Scopus subject areas

  • Clinical Neurology

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    Schuele, S. U., Kellinghaus, C., Shook, S. J., Boulis, N., Bethoux, F. A., & Loddenkemper, T. (2005). Incidence of seizures in patients with multiple sclerosis treated with intrathecal baclofen. Neurology, 64(6), 1086-1087. https://doi.org/10.1212/01.WNL.0000154639.35941.21