Incorporating human leukocyte antibody results into clinical practice

Anat R. Tambur*, Jacob Lavee

*Corresponding author for this work

Research output: Contribution to journalEditorial

10 Scopus citations

Abstract

The use of human leukocyte antigen (HLA) antibody testing by solid-phase assay has improved both the specificity and sensitivity of HLA antibody detection. It did, however, introduce questions regarding interpretation of crossmatch results in light of these additional data. Herein we provide a clinician's and a laboratory professional's perspective on incorporating HLA results into clinical practice. We strongly encourage fostering ongoing dialog between the two disciplines to develop appropriate, specific guidelines.

Original languageEnglish (US)
Pages (from-to)851-856
Number of pages6
JournalJournal of Heart and Lung Transplantation
Volume35
Issue number7
DOIs
StatePublished - Jul 1 2016

Keywords

  • HLA antibodies
  • donor specific antibodies
  • heart transplantation
  • solid-phase assays
  • virtual crossmatch

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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