Increased fibrinolytic activity in patients undergoing cardiopulmonary bypass operation

Omer Kucuk; Hau C. Kwaan; James Frederickson; Leonard Wade; David Green

doi:10.1002/ajh.2830230306

Increased fibrinolytic activity in patients undergoing cardiopulmonary bypass operation

Omer Kucuk^*, Hau C. Kwaan, James Frederickson, Leonard Wade, David Green

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

The influence of cardiopulmonary bypass on fibrinolytic activity was assessed by a sensitive clot lysis assay in eight patients undergoing coronary artery bypass operations. Fibrinolytic activity increased immediately after cardíopulmonary bypass was begun and remained elevated throughout the period of extracorporeal circulation. At the conclusion of the operative procedure, fibrinolytic activity returned to the normal range in all patients, and no subject had postoperative bleeding.

Original language	English (US)
Pages (from-to)	223-229
Number of pages	7
Journal	American Journal of Hematology
Volume	23
Issue number	3
DOIs	https://doi.org/10.1002/ajh.2830230306
State	Published - Nov 1986

Keywords

clot lysis assay
hemodilution
hypothermia

ASJC Scopus subject areas

Hematology

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10.1002/ajh.2830230306

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title = "Increased fibrinolytic activity in patients undergoing cardiopulmonary bypass operation",

abstract = "The influence of cardiopulmonary bypass on fibrinolytic activity was assessed by a sensitive clot lysis assay in eight patients undergoing coronary artery bypass operations. Fibrinolytic activity increased immediately after card{\'i}opulmonary bypass was begun and remained elevated throughout the period of extracorporeal circulation. At the conclusion of the operative procedure, fibrinolytic activity returned to the normal range in all patients, and no subject had postoperative bleeding.",

keywords = "clot lysis assay, hemodilution, hypothermia",

author = "Omer Kucuk and Kwaan, {Hau C.} and James Frederickson and Leonard Wade and David Green",

year = "1986",

month = nov,

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language = "English (US)",

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T1 - Increased fibrinolytic activity in patients undergoing cardiopulmonary bypass operation

AU - Kucuk, Omer

AU - Kwaan, Hau C.

AU - Frederickson, James

AU - Wade, Leonard

AU - Green, David

PY - 1986/11

Y1 - 1986/11

N2 - The influence of cardiopulmonary bypass on fibrinolytic activity was assessed by a sensitive clot lysis assay in eight patients undergoing coronary artery bypass operations. Fibrinolytic activity increased immediately after cardíopulmonary bypass was begun and remained elevated throughout the period of extracorporeal circulation. At the conclusion of the operative procedure, fibrinolytic activity returned to the normal range in all patients, and no subject had postoperative bleeding.

AB - The influence of cardiopulmonary bypass on fibrinolytic activity was assessed by a sensitive clot lysis assay in eight patients undergoing coronary artery bypass operations. Fibrinolytic activity increased immediately after cardíopulmonary bypass was begun and remained elevated throughout the period of extracorporeal circulation. At the conclusion of the operative procedure, fibrinolytic activity returned to the normal range in all patients, and no subject had postoperative bleeding.

KW - clot lysis assay

KW - hemodilution

KW - hypothermia

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U2 - 10.1002/ajh.2830230306

DO - 10.1002/ajh.2830230306

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JO - American Journal of Hematology

JF - American Journal of Hematology

IS - 3

ER -

Increased fibrinolytic activity in patients undergoing cardiopulmonary bypass operation

Abstract

Keywords

ASJC Scopus subject areas

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