Abstract
Transport of positive charge or holes in DNA occurs via a thermally activated multi-step hopping mechanism. The fastest hopping rates reported to date are those for repeating poly(purine) sequences in which hopping occurs via a random walk mechanism with rate constants of k hop = 4.3 ×10 9 s -1 for poly(dG) and 1.2 ×10 9 s -1 for poly(dA). We report here the dynamics of charge separation in DNA conjugates possessing repeating 7-deazaadenine (dzA) sequences. These data provide an estimated value of k hop = 4.2 ×10 10 s -1 for poly(dzA), an order of magnitude faster than for poly(dG).
Original language | English (US) |
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Pages (from-to) | 11485-11487 |
Number of pages | 3 |
Journal | Journal of the American Chemical Society |
Volume | 133 |
Issue number | 30 |
DOIs | |
State | Published - Aug 3 2011 |
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis
- Biochemistry
- Colloid and Surface Chemistry