Indications and complications of transfusions in sickle cell disease

Kim Smith-Whitley; Alexis A Thompson

doi:10.1002/pbc.24179

Indications and complications of transfusions in sickle cell disease

Kim Smith-Whitley^*, Alexis A Thompson

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

Red cell transfusion remains an important part of the management of acute and chronic complications in SCD. The ongoing and emerging uses of transfusions in SCD may have significant benefits; however, the potential complications of transfusions also deserve careful consideration. In this report we review current indications for transfusions, transfusion complications, modifications of transfusion practices to mitigate risk, and potential considerations to improve transfusion outcomes.

Original language	English (US)
Pages (from-to)	358-364
Number of pages	7
Journal	Pediatric Blood and Cancer
Volume	59
Issue number	2
DOIs	https://doi.org/10.1002/pbc.24179
State	Published - Aug 1 2012

Keywords

Alloimmunization
Red cell transfusion indications
Sickle cell disease
Transfusional iron overload

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1002/pbc.24179

Cite this

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abstract = "Red cell transfusion remains an important part of the management of acute and chronic complications in SCD. The ongoing and emerging uses of transfusions in SCD may have significant benefits; however, the potential complications of transfusions also deserve careful consideration. In this report we review current indications for transfusions, transfusion complications, modifications of transfusion practices to mitigate risk, and potential considerations to improve transfusion outcomes.",

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AB - Red cell transfusion remains an important part of the management of acute and chronic complications in SCD. The ongoing and emerging uses of transfusions in SCD may have significant benefits; however, the potential complications of transfusions also deserve careful consideration. In this report we review current indications for transfusions, transfusion complications, modifications of transfusion practices to mitigate risk, and potential considerations to improve transfusion outcomes.

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KW - Transfusional iron overload

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Indications and complications of transfusions in sickle cell disease

Abstract

Keywords

ASJC Scopus subject areas

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