Indications for liver transplantation in pediatric patients

P. F. Whitington*, J. C. Emond, D. D. Black, S. H. Whitington, P. Boone, C. Smith, J. R. Thistlethwaite, C. E. Broelsch

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Orthotopic liver transplantation has become a widely accepted therapy for children with end-stage liver disease. Several factors need to be kept in mind when advocating this procedure in pediatric patients. These include the following: (1) Liver transplantation is a high-risk procedure with a 10-15% mortality in the best of circumstances. (2) Recipients require long-term drug administration and have a potential for chronic disability. (3) The procedure is extremely expensive. (4) The long-term survival remains unknown. (5) Newer techniques and procedures need to be carefully evaluated. These factors, and the indications and contraindications for this procedure are discussed in this overview.

Original languageEnglish (US)
Pages (from-to)155-160
Number of pages6
JournalClinical Transplantation
Volume5
Issue number2 II
StatePublished - Jan 1 1991

Keywords

  • contraindications
  • indications
  • pediatric liver transplantation

ASJC Scopus subject areas

  • Transplantation

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