Induced Abortion for Genetic Indications: Techniques and Complications

Lee P. Shulman*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter focuses on the techniques, complications, and risks of abortion performed during the first and second trimesters of pregnancy. Chorionic villus sampling (CVS) and first-trimester endovaginal ultrasonography permit the cytogenetic and genomic assessment of the fetus in the first trimester. Detecting fetal disorders in the first trimester permits women to undergo first-trimester pregnancy termination, a procedure that is safer and less emotionally traumatic than termination performed later in pregnancy. Second-trimester pregnancy termination procedures have morbidity and mortality rates higher than first-trimester techniques. Some centers have begun to utilize preoperative or preinduction procedures to ensure the delivery of a demised fetus. Prior to dilation and evacuation (D and E), either a potassium chloride (KCl) intracardiac injection or umbilical cord avulsion can be performed, whereas a KCl intracardiac injection can be performed prior to initiation of systemic pharmacotherapy for a labor induction pregnancy termination.

Original languageEnglish (US)
Title of host publicationGenetic Disorders and the Fetus
Subtitle of host publicationDiagnosis, Prevention and Treatment: Seventh Edition
Number of pages20
ISBN (Electronic)9781118981559
ISBN (Print)9781118981528
StatePublished - Jan 1 2016


  • Chorionic villus sampling
  • Dilation and evacuation
  • Electric aspiration
  • First-trimester pregnancy termination
  • Induced abortion
  • Prenatal diagnosis
  • Second-trimester selective abortion
  • Selective abortion

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Induced Abortion for Genetic Indications: Techniques and Complications'. Together they form a unique fingerprint.

Cite this