Induced Hyponatremia for Sickle-Cell Crisis

Marshall Leary, Neil Abramson, Franklin H. Epstein, Robert M. Rosa, H. Franklin Bunn

Research output: Contribution to journalLetterpeer-review

9 Scopus citations


To the Editor: Dr. Rosa et al. are to be commended for their scientific report and cautious remarks on the treatment of three patients with sickle-cell anemia with induced hyponatremia (November 13 issue).* We have used the same therapy in four patients over the past year, since our early contacts with Dr. Rosa's group. We used the experience and data from the previous year (1979) as a control for the experience with hyponatremia in 1980. Our data confirm that hyponatremia can be induced in the hospital setting and that the use of desmopressin acetate (DDAVP) rather than vasopressin is essential.

Original languageEnglish (US)
Pages (from-to)844-845
Number of pages2
JournalNew England Journal of Medicine
Issue number14
StatePublished - Apr 2 1981

ASJC Scopus subject areas

  • General Medicine


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