Infants of diabetic mothers with accelerated fetal growth by ultrasonography: Are they all alike?

James D. Keller*, Boyd E. Metzger, Sharon L. Dooley, Ralph K. Tamura, Rudy E. Sabbagha, Norbert Freinkel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

We studied longitudinal ultrasonographic growth patterns (abdominal circumference, biparietal diameter) initiated early in gestation in 52 pregnancies complicated by pregestational diabetes mellitus and 19 controls. Three predominant patterns of growth were ascertained including a heretofore unrecognized pattern characterized by accelerated abdominal circumference growth (>90th percentlle) before 24 weeks' gestational age. Maternal and neonatal anthropometric and metabolic parameters were contrasted for the three patterns. The findings suggest that in some cases of diabetic macrosomia that can be recognized before 24 weeks' gestation, augmented growth may be influenced by factors other than fetal hyperinsulinism.

Original languageEnglish (US)
Pages (from-to)893-897
Number of pages5
JournalAmerican journal of obstetrics and gynecology
Volume163
Issue number3
DOIs
StatePublished - Sep 1990

Keywords

  • Evolving macrosomia
  • amniotic fluid insulin
  • diabetes mellitus

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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