Infectious (?) Myasthenia

S. K. Datta, R. S. Schwartz

Research output: Contribution to journalEditorial

35 Scopus citations

Abstract

Students of autoimmune diseases are witnessing a revolutionary movement that can be summarized by the difference between etiology and pathogenesis. Before the revolution, hazy images of “forbidden clones” and a faulty understanding of immunologic tolerance led to the assumption that autoimmunization was the etiology — the cause — of certain diseases. Now, however, the process of immunologic self-destruction seems better understood as a pathogenesis — i.e., as a mechanism that produces a lesion. The distinction that we draw is more than semantic. For example, there is abundant evidence from animal models that clinically silent, chronic viral infections can lead to.  . .

Original languageEnglish (US)
Pages (from-to)1304-1305
Number of pages2
JournalNew England Journal of Medicine
Volume291
Issue number24
DOIs
StatePublished - Dec 12 1974

ASJC Scopus subject areas

  • Medicine(all)

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