Infertility in female rabbits immunized with lactate dehydrogenase X

Erwin Goldberg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Immunization of female rabbits with the sperm-specific lactate dehydrogenase (LDH-X) resulted in a highly significant reduction of pregnancies compared to nonimmunized controls. This is the first demonstration of immunosuppression of fertility by a crystalline protein shown to be strictly homogeneous by ultracentrifugation, polyacrylamide gel electrophoresis, immunodiffusion, and micro complement fixation.

Original languageEnglish (US)
Pages (from-to)456-457
Number of pages2
JournalScience
Volume181
Issue number4098
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • Medicine(all)
  • General

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