Infertility in female rabbits immunized with lactate dehydrogenase X

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Immunization of female rabbits with the sperm specific lactate dehydrogenase (LDH X) resulted in a highly significant reduction of pregnancies compared to nonimmunized controls. This is the first demonstration of immunosuppression of fertility by a crystalline protein shown to be strictly homogeneous by ultracentrifugation, polyacrylamide gel electrophoresis, immunodiffusion, and micro complement fixation.

Original languageEnglish (US)
Pages (from-to)458-459
Number of pages2
Issue number4098
StatePublished - Jan 1 1973

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