Infertility in female rabbits immunized with lactate dehydrogenase X

Erwin Goldberg

doi:10.1126/science.181.4098.458

Infertility in female rabbits immunized with lactate dehydrogenase X

Erwin Goldberg

Molecular Biosciences

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Immunization of female rabbits with the sperm specific lactate dehydrogenase (LDH X) resulted in a highly significant reduction of pregnancies compared to nonimmunized controls. This is the first demonstration of immunosuppression of fertility by a crystalline protein shown to be strictly homogeneous by ultracentrifugation, polyacrylamide gel electrophoresis, immunodiffusion, and micro complement fixation.

Original language	English (US)
Pages (from-to)	458-459
Number of pages	2
Journal	Science
Volume	181
Issue number	4098
DOIs	https://doi.org/10.1126/science.181.4098.458
State	Published - Jan 1 1973

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abstract = "Immunization of female rabbits with the sperm specific lactate dehydrogenase (LDH X) resulted in a highly significant reduction of pregnancies compared to nonimmunized controls. This is the first demonstration of immunosuppression of fertility by a crystalline protein shown to be strictly homogeneous by ultracentrifugation, polyacrylamide gel electrophoresis, immunodiffusion, and micro complement fixation.",

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Infertility in female rabbits immunized with lactate dehydrogenase X

Abstract

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