Inflammatory breast cancer

Holly Dushkin*, Massimo Cristofanilli

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Inflammatory breast cancer (IBC) represents the most virulent form of breast cancer, characterized by involvement of the skin and rapid progression of the disease. Management involves careful coordination of multidisciplinary modalities, including imaging, systemic chemotherapy, surgery, and radiation therapy. The use of neoadjuvant chemotherapy has contributed significantly to improvement in overall survival since the first descriptions of this entity, and has made the role of locoregional therapy, including surgery and radiation, critical to continued improvements in this disease. This article examines the unique epidemiology and pathology of IBC, and reviews the various treatment modalities, noting the significance of a multimodality approach and delineating each of the specific components. Moreover, the current research in IBC is briefly described, which experts hope will further improve systemic therapies.

Original languageEnglish (US)
Pages (from-to)233-241
Number of pages9
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number2
StatePublished - Feb 1 2011


  • IBC
  • Inflammatory breast cancer
  • Locally advanced breast cancer
  • Multidisciplinary treatment

ASJC Scopus subject areas

  • Oncology


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