Inflammatory myofibroblastic tumor following hematopoietic stem cell transplantation: Report of two pediatric cases

J. Fangusaro, K. Klopfenstein, J. Groner, S. Hammond, R. A. Altura*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Inflammatory myofibroblastic tumors are benign neoplasms histologically composed of lymphocytes, histiocytes, macrophages, foam cells, and plasma cells among a spindle-shaped stroma. Their etiology and potential for metastatic spread is controversial. Numerous predisposing factors have been suggested, including preceding infections, radiotherapy, and local trauma. We present two cases of pseudotumors that developed in children following hematopoietic stem cell transplantation. These are the first cases after hematopoietic transplant reported in the literature. As these neoplasms are difficult to diagnose and are often confused with highly aggressive tumors, our cases demonstrate that a high index of suspicion for such lesions must be maintained when evaluating masses in post transplant patients.

Original languageEnglish (US)
Pages (from-to)103-107
Number of pages5
JournalBone Marrow Transplantation
Volume33
Issue number1
DOIs
StatePublished - Jan 2004

Keywords

  • Children
  • Inflammatory myofibroblastic tumor
  • Pseudotomor

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Fingerprint Dive into the research topics of 'Inflammatory myofibroblastic tumor following hematopoietic stem cell transplantation: Report of two pediatric cases'. Together they form a unique fingerprint.

Cite this