Influence of the k-space trajectory on the dynamic T1-weighted signal in quantitative first-pass cardiac perfusion MRI at 3T

Daniel Kim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The dynamic T1-weighted signal in first-pass myocardial perfusion MRI can vary as a function of it-space trajectory. The purpose of this study, therefore, was to compare the relative T1-weighted signal produced by the linear, centric, and reverse centric k-space trajectories at 3T. The centric k-space trajectory yielded higher arterial input function (AIF) than the linear and reverse centric k-space trajectories (6.21 ± 0.84 vs. 4.75 ± 0.75 vs. 4.39 ± 0.85 mM, respectively; N = 9; P < 0.01), and the reverse centric k-space trajectory yielded higher myocardial signal contrast (as a fraction of equilibrium magnetization) than the linear and centric k-space trajectories (0.17 ± 0.02 vs. 0.12 ± 0.02 vs. 0.05 ± 0.01, respectively; N = 9; P < 0.001). Compared to the linear k-space trajectory, the centric k-space trajectory is relatively optimal for the quantification of AIF, whereas the reverse centric k-space trajectory is relatively optimal for high contrast of myocardial wall enhancement.

Original languageEnglish (US)
Pages (from-to)202-208
Number of pages7
JournalMagnetic resonance in medicine
Volume59
Issue number1
DOIs
StatePublished - Jan 2008

Keywords

  • First-pass
  • Heart
  • MRI
  • Perfusion
  • Reordering
  • k-space trajectory

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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