Informed consent for live liver donors: A qualitative, prospective study

Elisa J. Gordon*, Jillian Rodde, Anton Skaro, Talia Baker

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Background & Aims Adult-to-adult live donor liver transplantation (LDLT) poses serious health risks and no direct health benefits to donors. Ensuring live donors' autonomy through informed consent is critical. We assessed live liver donors' (LD) comprehension, information needs, risk perceptions, and demographics. Methods Semi-structured interviews were prospectively conducted with LDs after completing donor evaluation and informed consent at our transplant center. Likert scales measured informed consent domains. Open-ended responses underwent thematic analysis. Results Thirty LDs participated (100% participation rate). Although 90% of LDs reported being informed about donation 'a great deal', only 66% reported understanding information about donation 'a great deal.' Many (40%) reported difficulty understanding medical terminology. Information LDs most desired to feel comfortable with their decision included: incidence and type of donor complications (67%), description of donation procedure (57%), and the process of donor preparation (43%). Most (83%) LDs rated risks to themselves as 'not at all' to 'somewhat' risky, and minimized these risks. Conclusions Although LDs perceived that they were adequately informed, their actual comprehension about donation was inadequate. Findings suggest the value of informed consent for preparation for the procedure and potential periprocedural risks rather than for decision-making. More comprehensible information disclosure may optimize informed consent.

Original languageEnglish (US)
Pages (from-to)838-847
Number of pages10
JournalJournal of Hepatology
Issue number4
StatePublished - Oct 1 2015


  • Bioethics
  • Education
  • Information needs
  • Informed consent
  • Liver transplantation
  • Qualitative research
  • Risk communication

ASJC Scopus subject areas

  • Hepatology


Dive into the research topics of 'Informed consent for live liver donors: A qualitative, prospective study'. Together they form a unique fingerprint.

Cite this