Inhalation anesthetics

Carly C. Guthrie, Jeffrey Lu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Halothane: a halogenated alkane compound that is a potent bronchodilator with very little pungency. For these reasons, it is extremely useful for inhalational inductions in children. Its MAC is 0.75 and its blood/gas partition coefficient is 2.4. It has the highest level of metabolization by the liver of any of the volatile anesthetics. The major metabolite is trifluoroacetic acid (TFA) and an immune-mediated reaction to this is the likely culprit for the hepatotoxicity that sometimes results, i.e., “halothane hepatitis.”

Original languageEnglish (US)
Title of host publicationEssential Clinical Anesthesia Review
Subtitle of host publicationKeywords, Questions and Answers for the Boards
PublisherCambridge University Press
Pages115-117
Number of pages3
ISBN (Electronic)9781139584005
ISBN (Print)9781107681309
DOIs
StatePublished - Jan 1 2015

Keywords

  • Altitude changes and vaporizer output
  • CO production
  • Changing vaporizers and vapor pressure
  • Compound A
  • Contraindications to nitrous oxide
  • Desflurane
  • Halothane
  • Isoflurane
  • Malignant hyperthermia
  • Nitrous oxide
  • Sevoflurane
  • Tec6 vaporizer

ASJC Scopus subject areas

  • Medicine(all)

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