Inhibin: Actions and signalling

David J. Phillips*, Teresa K. Woodruff

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

35 Scopus citations

Abstract

Inhibin is best known as a reproductive hormone that inhibits release of follicle-stimulating hormone (FSH) from the pituitary gland. Over the last decade or so a number of other biological roles have emerged, putting inhibin more in the class of a growth factor. Despite this, little is known of the signalling pathways for this protein. This minireview summarises the pertinent aspects of inhibin biology and focuses on four potential signalling mechanisms through which inhibin might influence cellular function, namely subunit availability, receptor assembly, co-receptors and signalling through inhibin-specific signalling pathways.

Original languageEnglish (US)
Pages (from-to)13-18
Number of pages6
JournalGrowth Factors
Volume22
Issue number1
DOIs
StatePublished - Mar 2004

Keywords

  • Activin
  • Betaglycan
  • Inhibin
  • Transforming growth factor-β

ASJC Scopus subject areas

  • Endocrinology
  • Clinical Biochemistry
  • Cell Biology

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