Inhibitory attentional control in patients with frontal lobe damage

Mariana Dimitrov; Marina Nakic; Jordan Elpern-Waxman; Joy Granetz; Joy O'Grady; Michael Phipps; Elizabeth Milne; Gordon D. Logan; Lynn Hasher; Jordan Grafman

doi:10.1016/S0278-2626(03)00080-0

Inhibitory attentional control in patients with frontal lobe damage

Mariana Dimitrov, Marina Nakic, Jordan Elpern-Waxman, Joy Granetz, Joy O'Grady, Michael Phipps, Elizabeth Milne, Gordon D. Logan, Lynn Hasher, Jordan Grafman^*

^*Corresponding author for this work

Physical Medicine and Rehabilitation

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control - the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.

Original language	English (US)
Pages (from-to)	258-270
Number of pages	13
Journal	Brain and cognition
Volume	52
Issue number	2
DOIs	https://doi.org/10.1016/S0278-2626(03)00080-0
State	Published - Jul 2003

Keywords

Attention
Inhibition
Negative priming
Prefrontal cortex
Stop-signal

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Experimental and Cognitive Psychology
Developmental and Educational Psychology
Arts and Humanities (miscellaneous)
Cognitive Neuroscience

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title = "Inhibitory attentional control in patients with frontal lobe damage",

abstract = "The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control - the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.",

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AU - Dimitrov, Mariana

AU - Nakic, Marina

AU - Elpern-Waxman, Jordan

AU - Granetz, Joy

AU - O'Grady, Joy

AU - Phipps, Michael

AU - Milne, Elizabeth

AU - Logan, Gordon D.

AU - Hasher, Lynn

AU - Grafman, Jordan

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N2 - The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control - the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.

AB - The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control - the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.

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KW - Inhibition

KW - Negative priming

KW - Prefrontal cortex

KW - Stop-signal

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Inhibitory attentional control in patients with frontal lobe damage

Abstract

Keywords

ASJC Scopus subject areas

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