TY - JOUR
T1 - Initial development and preliminary psychometric properties of the Prodromal Inventory of Negative Symptoms (PINS)
AU - Pelletier-Baldelli, Andrea
AU - Strauss, Gregory P.
AU - Visser, Katherine H.
AU - Mittal, Vijay A.
N1 - Funding Information:
This work was supported by the National Institute of Mental Health (F31MH100821-01A1 to A.P. and R01MH094650 and R21/33 MH103231 to V.A.M.).
Funding Information:
This work was supported by the National Institute of Mental Health ( F31MH100821-01A1 to A.P. and R01MH094650 and R21/33 MH103231 to V.A.M.). The authors thank Zachary Millman, Tina Gupta, Emily Carol and Derek Dean for their assistance with data collection and scale development. The authors would also like to acknowledge the CAINS and BNSS work groups for their large contribution to the field of negative symptoms assessment and in turn, impact on the development of the PINS.
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/11
Y1 - 2017/11
N2 - In the psychosis prodrome, sub-threshold positive symptoms are often preceded by negative symptoms. Individuals exhibiting these attenuated symptoms are primarily adolescents and young adults at clinical high-risk (CHR) for developing a psychotic disorder. In the CHR state, negative symptoms are highly predictive of the transition to diagnosable illness, making the assessment of these symptoms very important. Existing scales used to evaluate negative symptoms in this critical population are informative but have conceptual and psychometric limitations and/or were not designed according to modern conceptions delineated in the 2005 NIMH Negative Symptom Consensus Conference. The current study reports the development of the Prodromal Interview of Negative Symptoms (PINS) – a next-generation scale designed in accordance with the consensus conference recommendations. Preliminary data on the psychometric properties of the PINS is reported as part of ongoing scale development that will use a data-driven, iterative process to generate a final scale. Analysis of data from 53 CHR cases, 30 of whom were re-evaluated at 12 months, indicated that the beta version of the PINS demonstrated good internal consistency, inter-rater reliability, convergent validity, and discriminant validity. These preliminary findings provide direction for a revision of this measure, which resulted in the PINS-2, a promising new measure for the assessment of negative symptoms in CHR populations. This manuscript presents both the initial scale and resulting untested instrument, as well as a series of plans and recommendations for future development.
AB - In the psychosis prodrome, sub-threshold positive symptoms are often preceded by negative symptoms. Individuals exhibiting these attenuated symptoms are primarily adolescents and young adults at clinical high-risk (CHR) for developing a psychotic disorder. In the CHR state, negative symptoms are highly predictive of the transition to diagnosable illness, making the assessment of these symptoms very important. Existing scales used to evaluate negative symptoms in this critical population are informative but have conceptual and psychometric limitations and/or were not designed according to modern conceptions delineated in the 2005 NIMH Negative Symptom Consensus Conference. The current study reports the development of the Prodromal Interview of Negative Symptoms (PINS) – a next-generation scale designed in accordance with the consensus conference recommendations. Preliminary data on the psychometric properties of the PINS is reported as part of ongoing scale development that will use a data-driven, iterative process to generate a final scale. Analysis of data from 53 CHR cases, 30 of whom were re-evaluated at 12 months, indicated that the beta version of the PINS demonstrated good internal consistency, inter-rater reliability, convergent validity, and discriminant validity. These preliminary findings provide direction for a revision of this measure, which resulted in the PINS-2, a promising new measure for the assessment of negative symptoms in CHR populations. This manuscript presents both the initial scale and resulting untested instrument, as well as a series of plans and recommendations for future development.
KW - Assessment
KW - Negative symptoms
KW - Prodrome
KW - Psychosis risk
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U2 - 10.1016/j.schres.2017.01.055
DO - 10.1016/j.schres.2017.01.055
M3 - Article
C2 - 28189529
AN - SCOPUS:85011888114
SN - 0920-9964
VL - 189
SP - 43
EP - 49
JO - Schizophrenia Research
JF - Schizophrenia Research
ER -
