Initial experience with the Cosgrove-Edwards annuloplasty system

Delos M. Cosgrove*, Joseph M. Arcidi, Leonardo Rodriguez, William J. Stewart, Kimerly Powell, James D. Thomas

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

126 Scopus citations


Background.: The mitral valve has a nonplanar shape and a sphincter action. Pathologic dilatation occurs along the posterior annulus. To preserve the physiologic function and correct annular dilatation, we developed an annuloplasty system that is universally flexible and produces a measured plication of the posterior annulus (Cosgrove-Edwards Annuloplasty System). Methods.: The results of 150 consecutive mitral valve repairs using this system were analyzed. Mean age was 58 ± 13 years; 59% were men. The cause of the valve disease was degenerative in 75% of the patients, rheumatic in 13%, ischemic in 8%, and infectious in 4%. Associated procedures were performed in 61 patients (41%). Results.: Echocardiographic mitral regurgitation decreased from 3.7 ± 0.6 before repair to 0.2 ± 0.4 after repair (p < 0.0001). There were no hospital deaths and no cases of hemodynamically significant systolic anterior motion or other annuloplasty-related complications. Follow-up was 100% complete at a mean of 3.1 ± 3.6 months. There were three late deaths, three transient ischemic attacks, and one episode of endocarditis. Five patients (3.3%) have undergone reoperation for recurrent mitral insufficiency; no reoperations were related to the annuloplasty system. At a mean of 9 months, three-dimensional reconstruction of the mitral annulus from multiple echocardiographic images confirmed the nonplanar shape and sphincter mechanism of the annulus. Annular orifice area decreased 19% during the cardiac cycle from a mean of 10.3 cm2 in diastole to 8.6 cm2 in systole. Conclusions.: This annuloplasty system is effective for repair of insufficiency secondary to all causes, preserves physiologic annulus function, and is associated with a low incidence of valve-related complication.

Original languageEnglish (US)
Pages (from-to)499-504
Number of pages6
JournalThe Annals of thoracic surgery
Issue number3
StatePublished - Sep 1995

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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