Innervation zones of fasciculating motor units: Observations by a linear electrode array

Faezeh Jahanmiri-Nezhad*, Paul E. Barkhaus, William Z. Rymer, Ping Zhou

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


This study examines the innervation zone (IZ) in the biceps brachii muscle in healthy subjects and those with amyotrophic lateral sclerosis (ALS) using a 20-channel linear electromyogram (EMG) electrode array. Raster plots of individual waveform potentials were studied to estimate the motor unit IZ. While this work mainly focused on fasciculation potentials (FPs), a limited number of motor unit potentials (MUPs) from voluntary activity of 12 healthy and seven ALS subjects were also examined. Abnormal propagation of MUPs and scattered IZs were observed in fasciculating units, compared with voluntarily activated MUPs in healthy and ALS subjects. These findings can be related to muscle fiber reinnervation following motor neuron degeneration in ALS and the different origin sites of FPs compared with voluntary MUPs.

Original languageEnglish (US)
Article number239
JournalFrontiers in Human Neuroscience
Issue numberMAY
StatePublished - May 12 2015


  • ALS
  • Fasciculation potentials
  • Innervation zone
  • Linear array EMG electrode
  • Motor unit potentials
  • Reinnervation

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Behavioral Neuroscience


Dive into the research topics of 'Innervation zones of fasciculating motor units: Observations by a linear electrode array'. Together they form a unique fingerprint.

Cite this