Abstract
Primary liver tumors are most commonly hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Although surgical resection offers a chance for cure, these tumors generally present at a late, inoperable stage, necessitating an understanding of noncurative and palliative treatment options. These options include ablative therapies, including radiofrequency ablation; intra-arterial therapies, including transcatheter chemoembolization; biliary decompression; radiotherapy; systemic therapies, including traditional chemotherapeutic agents; and molecular therapies, such as sorafenib. Selection of nonoperative treatment depends on patient and tumor factors as well as institutional resources and expertise.
Original language | English (US) |
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Pages (from-to) | 745-762 |
Number of pages | 18 |
Journal | Surgical Oncology Clinics of North America |
Volume | 28 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2019 |
Externally published | Yes |
Keywords
- Ablative therapy
- Chemoembolization
- Cholangiocarcinoma
- Hepatocellular carcinoma
- Palliation
- Targeted therapies
ASJC Scopus subject areas
- Surgery
- Oncology