TY - JOUR

T1 - Integral calculus problem solving

T2 - An fMRI investigation

AU - Krueger, Frank

AU - Spampinato, Maria Vittoria

AU - Pardini, Matteo

AU - Pajevic, Sinisa

AU - Wood, Jacqueline N.

AU - Weiss, George H.

AU - Landgraf, Steffen

AU - Grafman, Jordan

PY - 2008/7/16

Y1 - 2008/7/16

N2 - Only a subset of adults acquires specific advanced mathematical skills, such as integral calculus. The representation of more sophisticated mathematical concepts probably evolved from basic number systems; however its neuroanatomical basis is still unknown. Using fMRI, we investigated the neural basis of integral calculus while healthy participants were engaged in an integration verification task. Solving integrals activated a left-lateralized cortical network including the horizontal intraparietal sulcus, posterior superior parietal lobe, posterior cingulate gyrus, and dorsolateral prefrontal cortex. Our results indicate that solving of more abstract and sophisticated mathematical facts, such as calculus integrals, elicits a pattern of brain activation similar to the cortical network engaged in basic numeric comparison, quantity manipulation, and arithmetic problem solving.

AB - Only a subset of adults acquires specific advanced mathematical skills, such as integral calculus. The representation of more sophisticated mathematical concepts probably evolved from basic number systems; however its neuroanatomical basis is still unknown. Using fMRI, we investigated the neural basis of integral calculus while healthy participants were engaged in an integration verification task. Solving integrals activated a left-lateralized cortical network including the horizontal intraparietal sulcus, posterior superior parietal lobe, posterior cingulate gyrus, and dorsolateral prefrontal cortex. Our results indicate that solving of more abstract and sophisticated mathematical facts, such as calculus integrals, elicits a pattern of brain activation similar to the cortical network engaged in basic numeric comparison, quantity manipulation, and arithmetic problem solving.

KW - Arithmetic

KW - Dorsolateral prefrontal cortex

KW - Intraparietal sulcus

KW - Mathematics

KW - Superior parietal lobe

UR - http://www.scopus.com/inward/record.url?scp=49949115092&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49949115092&partnerID=8YFLogxK

U2 - 10.1097/WNR.0b013e328303fd85

DO - 10.1097/WNR.0b013e328303fd85

M3 - Article

C2 - 18596607

AN - SCOPUS:49949115092

VL - 19

SP - 1095

EP - 1099

JO - NeuroReport

JF - NeuroReport

SN - 0959-4965

IS - 11

ER -