Integrated MOSFET-embedded-cantilever-based biosensor characteristic for detection of anthrax simulant

Salwa Mostafa; Ida Lee; Syed K. Islam; Sazia A. Eliza; Gajendra Shekhawat; Vinayak P. Dravid; Fahmida S. Tulip

doi:10.1109/LED.2010.2098015

Integrated MOSFET-embedded-cantilever-based biosensor characteristic for detection of anthrax simulant

Salwa Mostafa^*, Ida Lee, Syed K. Islam, Sazia A. Eliza, Gajendra Shekhawat, Vinayak P. Dravid, Fahmida S. Tulip

^*Corresponding author for this work

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

In this work, MOSFET-embedded cantilevers are configured as microbial sensors for detection of anthrax simulants, Bacillus thuringiensis. Anthrax simulants attached to the chemically treated gold-coated cantilever cause changes in the MOSFET drain current due to the bending of the cantilever which indicates the detection of anthrax simulant. Electrical properties of the anthrax simulant are also responsible for the change in the drain current. The test results suggest a detection range of 10 μL of stimulant test solution (a suspension population of 1.3×10^-7 colony-forming units/mL diluted in 40% ethanol and 60% deionized water) with a linear response of 31 μAμL.

Original language	English (US)
Article number	5680937
Pages (from-to)	408-410
Number of pages	3
Journal	IEEE Electron Device Letters
Volume	32
Issue number	3
DOIs	https://doi.org/10.1109/LED.2010.2098015
State	Published - Mar 2011

Keywords

Anthrax simulant
MOSFET-embedded cantilever
biosensor

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering

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10.1109/LED.2010.2098015

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title = "Integrated MOSFET-embedded-cantilever-based biosensor characteristic for detection of anthrax simulant",

abstract = "In this work, MOSFET-embedded cantilevers are configured as microbial sensors for detection of anthrax simulants, Bacillus thuringiensis. Anthrax simulants attached to the chemically treated gold-coated cantilever cause changes in the MOSFET drain current due to the bending of the cantilever which indicates the detection of anthrax simulant. Electrical properties of the anthrax simulant are also responsible for the change in the drain current. The test results suggest a detection range of 10 μL of stimulant test solution (a suspension population of 1.3×10-7 colony-forming units/mL diluted in 40% ethanol and 60% deionized water) with a linear response of 31 μAμL.",

keywords = "Anthrax simulant, MOSFET-embedded cantilever, biosensor",

author = "Salwa Mostafa and Ida Lee and Islam, {Syed K.} and Eliza, {Sazia A.} and Gajendra Shekhawat and Dravid, {Vinayak P.} and Tulip, {Fahmida S.}",

note = "Funding Information: Manuscript received October 30, 2010; revised November 22, 2010; accepted November 25, 2010. Date of publication January 6, 2011; date of current version February 23, 2011. This work was supported in part by the National Science Foundation under Award ID 0330410. The review of this letter was arranged by Editor J. K. O. Sin.",

year = "2011",

month = mar,

doi = "10.1109/LED.2010.2098015",

language = "English (US)",

volume = "32",

pages = "408--410",

journal = "IEEE Electron Device Letters",

issn = "0741-3106",

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Integrated MOSFET-embedded-cantilever-based biosensor characteristic for detection of anthrax simulant. / Mostafa, Salwa; Lee, Ida; Islam, Syed K.; Eliza, Sazia A.; Shekhawat, Gajendra ; Dravid, Vinayak P.; Tulip, Fahmida S.

In: IEEE Electron Device Letters, Vol. 32, No. 3, 5680937, 03.2011, p. 408-410.

Research output: Contribution to journal › Article › peer-review

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AU - Mostafa, Salwa

AU - Lee, Ida

AU - Islam, Syed K.

AU - Eliza, Sazia A.

AU - Shekhawat, Gajendra

AU - Dravid, Vinayak P.

AU - Tulip, Fahmida S.

N1 - Funding Information: Manuscript received October 30, 2010; revised November 22, 2010; accepted November 25, 2010. Date of publication January 6, 2011; date of current version February 23, 2011. This work was supported in part by the National Science Foundation under Award ID 0330410. The review of this letter was arranged by Editor J. K. O. Sin.

PY - 2011/3

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Integrated MOSFET-embedded-cantilever-based biosensor characteristic for detection of anthrax simulant

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Keywords

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