Integration of Metal-Organic Frameworks on Protective Layers for Destruction of Nerve Agents under Relevant Conditions

Zhijie Chen; Kaikai Ma; John J. Mahle; Hui Wang; Zoha H. Syed; Ahmet Atilgan; Yongwei Chen; John H. Xin; Timur Islamoglu; Gregory W. Peterson; Omar K. Farha

doi:10.1021/jacs.9b11172

Integration of Metal-Organic Frameworks on Protective Layers for Destruction of Nerve Agents under Relevant Conditions

Zhijie Chen, Kaikai Ma, John J. Mahle, Hui Wang, Zoha H. Syed, Ahmet Atilgan, Yongwei Chen, John H. Xin, Timur Islamoglu, Gregory W. Peterson, Omar K. Farha^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

130 Scopus citations

Abstract

Metal-organic frameworks (MOFs) are promising candidates for the catalytic hydrolysis of nerve agents and their simulants. Though highly efficient, bulk water and volatile bases are often required for hydrolysis with these MOF catalysts, preventing real-world implementation. Herein we report a generalizable and scalable approach for integrating MOFs and non-volatile polymeric bases onto textile fibers for nerve agent hydrolysis. Notably, the composite material showed similar reactivity under ambient conditions compared to the powder material in aqueous alkaline solution. This represents a critical step toward a unified strategy for nerve agent hydrolysis in practical settings, which can significantly reduce the dimensions of filters and increase the efficiency of protective suits.

Original language	English (US)
Pages (from-to)	20016-20021
Number of pages	6
Journal	Journal of the American Chemical Society
Volume	141
Issue number	51
DOIs	https://doi.org/10.1021/jacs.9b11172
State	Published - Dec 26 2019

Funding

O.K.F. gratefully acknowledges support from the Defense Threat Reduction Agency (HDTRA1-18-1-0003). G.W.P., J.J.M., and H.W. gratefully acknowledge support from the Defense Threat Reduction Agency under Grant CB3934 for the hydrolysis of GD. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. (DGE-1842165) (Z.H.S.). The authors thank Alyssa Olszewski for assistance in making schemes. The authors acknowledge Morgan Hall and Eric Bruni for the NMR support. This work made use of the EPIC facility of Northwestern University’s NUANCE Center, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF NNCI-1542205); the MRSEC program (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; and the State of Illinois, through the IIN. This work made use of the IMSERC at Northwestern University, which has received support from the NSF (CHE-1048773 and DMR0521267); Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF NNCI-1542205); and the State of Illinois and International Institute for Nanotechnology (IIN).

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/jacs.9b11172

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title = "Integration of Metal-Organic Frameworks on Protective Layers for Destruction of Nerve Agents under Relevant Conditions",

abstract = "Metal-organic frameworks (MOFs) are promising candidates for the catalytic hydrolysis of nerve agents and their simulants. Though highly efficient, bulk water and volatile bases are often required for hydrolysis with these MOF catalysts, preventing real-world implementation. Herein we report a generalizable and scalable approach for integrating MOFs and non-volatile polymeric bases onto textile fibers for nerve agent hydrolysis. Notably, the composite material showed similar reactivity under ambient conditions compared to the powder material in aqueous alkaline solution. This represents a critical step toward a unified strategy for nerve agent hydrolysis in practical settings, which can significantly reduce the dimensions of filters and increase the efficiency of protective suits.",

author = "Zhijie Chen and Kaikai Ma and Mahle, {John J.} and Hui Wang and Syed, {Zoha H.} and Ahmet Atilgan and Yongwei Chen and Xin, {John H.} and Timur Islamoglu and Peterson, {Gregory W.} and Farha, {Omar K.}",

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AU - Chen, Zhijie

AU - Ma, Kaikai

AU - Mahle, John J.

AU - Wang, Hui

AU - Syed, Zoha H.

AU - Atilgan, Ahmet

AU - Chen, Yongwei

AU - Xin, John H.

AU - Islamoglu, Timur

AU - Peterson, Gregory W.

AU - Farha, Omar K.

PY - 2019/12/26

Y1 - 2019/12/26

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AB - Metal-organic frameworks (MOFs) are promising candidates for the catalytic hydrolysis of nerve agents and their simulants. Though highly efficient, bulk water and volatile bases are often required for hydrolysis with these MOF catalysts, preventing real-world implementation. Herein we report a generalizable and scalable approach for integrating MOFs and non-volatile polymeric bases onto textile fibers for nerve agent hydrolysis. Notably, the composite material showed similar reactivity under ambient conditions compared to the powder material in aqueous alkaline solution. This represents a critical step toward a unified strategy for nerve agent hydrolysis in practical settings, which can significantly reduce the dimensions of filters and increase the efficiency of protective suits.

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Integration of Metal-Organic Frameworks on Protective Layers for Destruction of Nerve Agents under Relevant Conditions

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