Integrative internet-based depression prevention for adolescents: A randomized clinical trial in primary care for vulnerability and protective factors

Benjamine W. Van Voorhees*, Karen Vanderplough-Booth, Joshua Fogel, Tracy Gladstone, Carl Bell, Scott Stuart, Jacqueline K Gollan, Nathan Bradford, Rocco Domanico, Blake Fagan, Ruth Ross, Jon Larson, Natalie Watson, Dave Paunesku, Stephanie Melkonian, Sachiko Kuwabara, Tim Holper, Nicholas Shank, Donald Saner, Amy ButlerAmy Chandler, Tina Louie, Cynthia Weinstein, Shannon Collins, Melinda Baldwin, Abigail Wassel, Mark A Reinecke

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

Background: Adolescent depression is both a major public health and clinical problem, yet primary care physicians have limited intervention options. We developed two versions of an Internet-based behavioral intervention to prevent the onset of major depression and compared them in a randomized clinical trial in 13 US primary care practices. Methods: We enrolled 84 adolescents at risk for developing major depression and randomly assigned them to two groups: brief advice (BA; 1-2 minutes) + Internet program versus motivational interview (MI; 5-15 minutes) + Internet program. We compared pre/post changes and between group differences for protective and vulnerability factors (individual, family, school and peer). Results: Compared with pre-study values, both groups demonstrated declines in depressed mood; [MI: 21.2 to 16.74 (p < 0.01), BA: 23.34 to 16.92 (p < 0.001)]. Similarly, both groups demonstrated increases in social support by peers [MI: 8.6 to 12.1 (p = 0.002), BA: 7.10 to 12.5 (p < 0.001)] and reductions in depression related impairment in school [MI: 2.26 to 1.76 (p = 0.06), BA: 2.16 to 1.93 (p = 0.07)]. Conclusions: Two forms of a primary care/Internet-based behavioral intervention to prevent adolescent depression may lower depressed mood and strengthen some protective factors for depression.

Original languageEnglish (US)
Pages (from-to)184-196
Number of pages13
JournalJournal of the Canadian Academy of Child and Adolescent Psychiatry
Volume17
Issue number4
StatePublished - 2008

Keywords

  • Adolescents
  • Depressive disorder
  • Internet
  • Intervention
  • Prevention
  • Primary care

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health

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