Intensity Dependent Long-Term Potentiation and Inhibition in Paired Associated Stimulation by Transcranial Magnetic Stimulation: A Pilot Study

A. San Agustín*, D. Crevillén, A. Oliviero, José L. Pons, J. C. Moreno

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The Paired Associated Stimulation (PAS) protocol has been probed to successfully induce motor cortico-spinal plasticity. However, there is not an official consensus for the optimal Transcranial Magnetic Stimulation (TMS) intensity in PAS applications. The aim of this pilot study is to research the implication of intensity factor during the plasticity induction by PAS in later excitability assessment through each measurable intensity (90, 100, 110, 120 and 130% of the rMT). The results point to a conditioning of the intensity on the Motor Evoked Potentials (MEPs) towards a polarized outcome between high and low frequencies. Regardless, a complete research would be necessary to determine the impact extent of the PAS intensity factor.

Original languageEnglish (US)
Title of host publicationBiosystems and Biorobotics
PublisherSpringer Science and Business Media Deutschland GmbH
Pages771-776
Number of pages6
DOIs
StatePublished - 2022

Publication series

NameBiosystems and Biorobotics
Volume28
ISSN (Print)2195-3562
ISSN (Electronic)2195-3570

ASJC Scopus subject areas

  • Biomedical Engineering
  • Mechanical Engineering
  • Artificial Intelligence

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