Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay

Qi L. Xiong, Xiao Y. Wu, Jun Yao, Theresa Sukal Moulton, Nong Xiao, Lin Chen, Xiao L. Zheng, Yuan Liu, Wen S. Hou*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The aim of this study was to quantify and compare the inter-limb muscle coordination during crawling between typically developing infants and infants with developmental delay. Typically developing (TD, \text{N}=20) infants and infants with at risk of developmental delay (ARDD, \textbf{N}=33) or confirmed developmental delayCDD, N=14) participated in this study. Surface electromyography of eight muscles from arms and legs and the corresponding joint kinematic data were collected while they were crawling on hands and knees at their self-selected velocity. The number of used inter-limb muscle synergies during crawling was identified by nonnegative matrix factorization algorithm. Our results showed that there was no significant difference in the number of used muscle synergies between ARDD and TD infants during crawling. However, a reduced number of synergies were identified in infants with CDD, as compared to that in TD and ARDD infants, indicating constrained neuromuscular control strategy during crawling in developmental delayed infants. The absence of inter-limb muscle synergies may be one of the mechanisms underlying the impairments of crawling in developmental delayed infants, who are at high risk of cerebral palsy. This result also suggests that the metrics of muscle synergy during infant crawling, such as the number of synergy, may be feasible as a biomarker for early diagnosis of infants with cerebral palsy.

Original languageEnglish (US)
Title of host publication40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4697-4700
Number of pages4
ISBN (Electronic)9781538636466
DOIs
StatePublished - Oct 26 2018
Event40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States
Duration: Jul 18 2018Jul 21 2018

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2018-July
ISSN (Print)1557-170X

Other

Other40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
CountryUnited States
CityHonolulu
Period7/18/187/21/18

Fingerprint

Muscle
Knee
Extremities
Hand
Muscles
Electromyography
Cerebral Palsy
Biomarkers
Factorization
Kinematics
Biomechanical Phenomena
Early Diagnosis
Leg
Arm
Joints

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Xiong, Q. L., Wu, X. Y., Yao, J., Sukal Moulton, T., Xiao, N., Chen, L., ... Hou, W. S. (2018). Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 (pp. 4697-4700). [8513123] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2018-July). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2018.8513123
Xiong, Qi L. ; Wu, Xiao Y. ; Yao, Jun ; Sukal Moulton, Theresa ; Xiao, Nong ; Chen, Lin ; Zheng, Xiao L. ; Liu, Yuan ; Hou, Wen S. / Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 4697-4700 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).
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title = "Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay",
abstract = "The aim of this study was to quantify and compare the inter-limb muscle coordination during crawling between typically developing infants and infants with developmental delay. Typically developing (TD, \text{N}=20) infants and infants with at risk of developmental delay (ARDD, \textbf{N}=33) or confirmed developmental delayCDD, N=14) participated in this study. Surface electromyography of eight muscles from arms and legs and the corresponding joint kinematic data were collected while they were crawling on hands and knees at their self-selected velocity. The number of used inter-limb muscle synergies during crawling was identified by nonnegative matrix factorization algorithm. Our results showed that there was no significant difference in the number of used muscle synergies between ARDD and TD infants during crawling. However, a reduced number of synergies were identified in infants with CDD, as compared to that in TD and ARDD infants, indicating constrained neuromuscular control strategy during crawling in developmental delayed infants. The absence of inter-limb muscle synergies may be one of the mechanisms underlying the impairments of crawling in developmental delayed infants, who are at high risk of cerebral palsy. This result also suggests that the metrics of muscle synergy during infant crawling, such as the number of synergy, may be feasible as a biomarker for early diagnosis of infants with cerebral palsy.",
author = "Xiong, {Qi L.} and Wu, {Xiao Y.} and Jun Yao and {Sukal Moulton}, Theresa and Nong Xiao and Lin Chen and Zheng, {Xiao L.} and Yuan Liu and Hou, {Wen S.}",
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Xiong, QL, Wu, XY, Yao, J, Sukal Moulton, T, Xiao, N, Chen, L, Zheng, XL, Liu, Y & Hou, WS 2018, Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay. in 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018., 8513123, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2018-July, Institute of Electrical and Electronics Engineers Inc., pp. 4697-4700, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018, Honolulu, United States, 7/18/18. https://doi.org/10.1109/EMBC.2018.8513123

Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay. / Xiong, Qi L.; Wu, Xiao Y.; Yao, Jun; Sukal Moulton, Theresa; Xiao, Nong; Chen, Lin; Zheng, Xiao L.; Liu, Yuan; Hou, Wen S.

40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 4697-4700 8513123 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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T1 - Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay

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AU - Yao, Jun

AU - Sukal Moulton, Theresa

AU - Xiao, Nong

AU - Chen, Lin

AU - Zheng, Xiao L.

AU - Liu, Yuan

AU - Hou, Wen S.

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N2 - The aim of this study was to quantify and compare the inter-limb muscle coordination during crawling between typically developing infants and infants with developmental delay. Typically developing (TD, \text{N}=20) infants and infants with at risk of developmental delay (ARDD, \textbf{N}=33) or confirmed developmental delayCDD, N=14) participated in this study. Surface electromyography of eight muscles from arms and legs and the corresponding joint kinematic data were collected while they were crawling on hands and knees at their self-selected velocity. The number of used inter-limb muscle synergies during crawling was identified by nonnegative matrix factorization algorithm. Our results showed that there was no significant difference in the number of used muscle synergies between ARDD and TD infants during crawling. However, a reduced number of synergies were identified in infants with CDD, as compared to that in TD and ARDD infants, indicating constrained neuromuscular control strategy during crawling in developmental delayed infants. The absence of inter-limb muscle synergies may be one of the mechanisms underlying the impairments of crawling in developmental delayed infants, who are at high risk of cerebral palsy. This result also suggests that the metrics of muscle synergy during infant crawling, such as the number of synergy, may be feasible as a biomarker for early diagnosis of infants with cerebral palsy.

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Xiong QL, Wu XY, Yao J, Sukal Moulton T, Xiao N, Chen L et al. Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay. In 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 4697-4700. 8513123. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2018.8513123