TY - GEN
T1 - Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental Delay
AU - Xiong, Qi L.
AU - Wu, Xiao Y.
AU - Yao, Jun
AU - Sukal, Theresa M.
AU - Xiao, Nong
AU - Chen, Lin
AU - Zheng, Xiao L.
AU - Liu, Yuan
AU - Hou, Wen S.
N1 - Funding Information:
* This work was supported by the National Natural Science Foundation of China (31470953, 31771069), the National High-Tech Research and Development Program (863 Program) of China (2015AA042303), and the Chongqing Science & Technology Program (cstc2016shmszx130060, cstc2015jcyjB0538). Corresponding to: Wen S. Hou (e-mail: w.s.hou@cqu.edu.cn) Qi L. Xiong, Xiao Y. Wu and Lin Chen are with the Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering college, Chongqing University, Chongqing 400044, China.
Funding Information:
This work was supported by the National Natural Science Foundation of China (31470953, 31771069), the National High-Tech Research and Development Program (863 Program) of China (2015AA042303), and the Chongqing Science & Technology Program (cstc2016shmszx130060, cstc2015jcyjB0538).
PY - 2018/10/26
Y1 - 2018/10/26
N2 - The aim of this study was to quantify and compare the inter-limb muscle coordination during crawling between typically developing infants and infants with developmental delay. Typically developing (TD, \text{N}=20) infants and infants with at risk of developmental delay (ARDD, \textbf{N}=33) or confirmed developmental delayCDD, N=14) participated in this study. Surface electromyography of eight muscles from arms and legs and the corresponding joint kinematic data were collected while they were crawling on hands and knees at their self-selected velocity. The number of used inter-limb muscle synergies during crawling was identified by nonnegative matrix factorization algorithm. Our results showed that there was no significant difference in the number of used muscle synergies between ARDD and TD infants during crawling. However, a reduced number of synergies were identified in infants with CDD, as compared to that in TD and ARDD infants, indicating constrained neuromuscular control strategy during crawling in developmental delayed infants. The absence of inter-limb muscle synergies may be one of the mechanisms underlying the impairments of crawling in developmental delayed infants, who are at high risk of cerebral palsy. This result also suggests that the metrics of muscle synergy during infant crawling, such as the number of synergy, may be feasible as a biomarker for early diagnosis of infants with cerebral palsy.
AB - The aim of this study was to quantify and compare the inter-limb muscle coordination during crawling between typically developing infants and infants with developmental delay. Typically developing (TD, \text{N}=20) infants and infants with at risk of developmental delay (ARDD, \textbf{N}=33) or confirmed developmental delayCDD, N=14) participated in this study. Surface electromyography of eight muscles from arms and legs and the corresponding joint kinematic data were collected while they were crawling on hands and knees at their self-selected velocity. The number of used inter-limb muscle synergies during crawling was identified by nonnegative matrix factorization algorithm. Our results showed that there was no significant difference in the number of used muscle synergies between ARDD and TD infants during crawling. However, a reduced number of synergies were identified in infants with CDD, as compared to that in TD and ARDD infants, indicating constrained neuromuscular control strategy during crawling in developmental delayed infants. The absence of inter-limb muscle synergies may be one of the mechanisms underlying the impairments of crawling in developmental delayed infants, who are at high risk of cerebral palsy. This result also suggests that the metrics of muscle synergy during infant crawling, such as the number of synergy, may be feasible as a biomarker for early diagnosis of infants with cerebral palsy.
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U2 - 10.1109/EMBC.2018.8513123
DO - 10.1109/EMBC.2018.8513123
M3 - Conference contribution
C2 - 30441398
AN - SCOPUS:85056672958
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 4697
EP - 4700
BT - 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
Y2 - 18 July 2018 through 21 July 2018
ER -