Internal radioembolization for colorectal carcinoma liver metastases

Saad M. Ibrahim, Ahsun Riaz, Robert J. Lewandowski, Mary F. Mulcahy, Al B. Benson, Riad Salem*

*Corresponding author for this work

Research output: Contribution to journalReview article

Abstract

Colorectal cancer remains a significant cause of morbidity and mortality. Treatment options and therapeutic interventions for patients who have disease progression despite treatment with systemic therapies have not been clearly established. However, yttrium-90 radioembolization may be useful as a minimally invasive liver-directed therapy. Although there are no large randomized controlled studies that specifically establish the role of radioembolization in this patient population, numerous studies have shown favorable toxicity and efficacy profiles and promising overall survival.

Original languageEnglish (US)
Pages (from-to)93-98
Number of pages6
JournalCurrent Colorectal Cancer Reports
Volume5
Issue number2
DOIs
StatePublished - Apr 1 2009

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Colorectal Neoplasms
Neoplasm Metastasis
Liver
Therapeutics
Yttrium
Disease Progression
Morbidity
Survival
Mortality
Population

ASJC Scopus subject areas

  • Hepatology
  • Oncology
  • Gastroenterology

Cite this

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abstract = "Colorectal cancer remains a significant cause of morbidity and mortality. Treatment options and therapeutic interventions for patients who have disease progression despite treatment with systemic therapies have not been clearly established. However, yttrium-90 radioembolization may be useful as a minimally invasive liver-directed therapy. Although there are no large randomized controlled studies that specifically establish the role of radioembolization in this patient population, numerous studies have shown favorable toxicity and efficacy profiles and promising overall survival.",
author = "Ibrahim, {Saad M.} and Ahsun Riaz and Lewandowski, {Robert J.} and Mulcahy, {Mary F.} and Benson, {Al B.} and Riad Salem",
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AU - Riaz, Ahsun

AU - Lewandowski, Robert J.

AU - Mulcahy, Mary F.

AU - Benson, Al B.

AU - Salem, Riad

PY - 2009/4/1

Y1 - 2009/4/1

N2 - Colorectal cancer remains a significant cause of morbidity and mortality. Treatment options and therapeutic interventions for patients who have disease progression despite treatment with systemic therapies have not been clearly established. However, yttrium-90 radioembolization may be useful as a minimally invasive liver-directed therapy. Although there are no large randomized controlled studies that specifically establish the role of radioembolization in this patient population, numerous studies have shown favorable toxicity and efficacy profiles and promising overall survival.

AB - Colorectal cancer remains a significant cause of morbidity and mortality. Treatment options and therapeutic interventions for patients who have disease progression despite treatment with systemic therapies have not been clearly established. However, yttrium-90 radioembolization may be useful as a minimally invasive liver-directed therapy. Although there are no large randomized controlled studies that specifically establish the role of radioembolization in this patient population, numerous studies have shown favorable toxicity and efficacy profiles and promising overall survival.

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