Colorectal cancer remains a significant cause of morbidity and mortality. Treatment options and therapeutic interventions for patients who have disease progression despite treatment with systemic therapies have not been clearly established. However, yttrium-90 radioembolization may be useful as a minimally invasive liver-directed therapy. Although there are no large randomized controlled studies that specifically establish the role of radioembolization in this patient population, numerous studies have shown favorable toxicity and efficacy profiles and promising overall survival.
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