International collaborative study on EUS-guided gallbladder drainage: Are we ready for prime time?

Michel Kahaleh*, Manuel Perez-Miranda, Everson L. Artifon, Reem Z. Sharaiha, Prashant Kedia, Irene Peñas, Carlos De la Serna, Nikhil A. Kumta, Fernando Marson, Monica Gaidhane, Christine Boumitri, Viviana Parra, Carlos M. Rondon Clavo, Marc Giovannini

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Background Cholecystectomy remains the gold standard treatment of cholecystitis. Endoscopic treatment of cholecystitis includes transpapillary gallbladder drainage. Recently, endoscopic ultrasound-guided transmural drainage of the gallbladder (EUS-GBD) has been reported. This study reports the cumulative experience of an international group performing EUS-GBD. Methods Cases of EUS-GBD from January 2012 to November 2013 from 3 tertiary-care institutions were captured in a registry. Patient demographics, disease characteristics, procedural and clinical outcomes were recorded. Results 35 patients (15 malignant, 20 benign) were included. Median age was 81 years (SD = 13.76 years), sixteen (46%) were males. Median follow-up was 91.5 days (SD = 157 days). Transmural access was obtained from the stomach (n = 17) or duodenum (n = 18). Stents placed included plastic (n = 6), metal (n = 20), or combination (n = 7). Technical success was achieved in 91.4% (n = 32). Immediate adverse events (14%) included: bleeding, stent migration, cholecystitis and hemoperitoneum. Delayed adverse events (11%) included abscess formation and recurrence of cholecystitis. Long-term clinical success rate was 89%. Stent type and puncture site were not associated with immediate (p = 0.88, p = 0.62), or long-term (p = 0.47, p = 0.27) success. Conclusions EUS-GBD appears to be feasible, safe, and effective. Prospective studies are needed to confirm these findings and identify the best technique to use. Clinical trial registration NCT01522573.

Original languageEnglish (US)
Pages (from-to)1054-1057
Number of pages4
JournalDigestive and Liver Disease
Issue number9
StatePublished - Sep 1 2016


  • Cholecytitis
  • Endoscopic gallbladder drainage
  • Endoscopic ultrasound
  • EUS
  • Gallbladder drainage

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


Dive into the research topics of 'International collaborative study on EUS-guided gallbladder drainage: Are we ready for prime time?'. Together they form a unique fingerprint.

Cite this