Interpenetration Isomerism in Triptycene-Based Hydrogen-Bonded Organic Frameworks

Penghao Li, Peng Li, Matthew R. Ryder, Zhichang Liu, Charlotte L. Stern, Omar K. Farha, J. Fraser Stoddart*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


We describe an example of “interpenetration isomerism” in three-dimensional hydrogen-bonded organic frameworks. By exploiting the crystallization conditions for a peripherally extended triptycene H 6 PET, we can modulate the interpenetration of the assembled frameworks, yielding a two-fold interpenetrated structure PETHOF-1 and a five-fold interpenetrated structure PETHOF-2 as interpenetration isomers. In PETHOF-1, two individual nets are related by inversion symmetry and form an interwoven topology with a large guest-accessible volume of about 80 %. In PETHOF-2, five individual nets are related by translational symmetry and are stacked in an alternating fashion. The activated materials show permanent porosity with Brunauer-Emmett-Teller surface areas exceeding 1100 m 2 g −1 . Synthetic control over the framework interpenetration could serve as a new strategy to construct complex supramolecular architectures from simple organic building blocks.

Original languageEnglish (US)
Pages (from-to)1664-1669
Number of pages6
JournalAngewandte Chemie - International Edition
Issue number6
StatePublished - Feb 4 2019


  • crystal engineering
  • hydrogen-bonded organic frameworks
  • interpenetration isomerism
  • porous molecular solids
  • supramolecular chemistry

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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