Interpretation and management of hepatic abnormalities in pregnancy

Leila Kia, Mary E. Rinella*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The spectrum of liver disease in pregnancy includes liver disease unrelated to pregnancy, liver diseases that occur with increased frequency or severity in pregnancy, and liver disease specific to pregnancy. Diseases of the liver unique to pregnancy reliably occur at specific points in the gestational spectrum. Thus, gestational age, a comprehensive history, and a clinically driven diagnostic evaluation is critical in approaching a pregnant patient with abnormal liver chemistries or function. Early recognition of these conditions is important and although management may be expectant, some patients require targeted therapy or necessitate prompt delivery, which can be life-saving to both mother and child.

Original languageEnglish (US)
Pages (from-to)1392-1398
Number of pages7
JournalClinical Gastroenterology and Hepatology
Issue number11
StatePublished - Nov 2013


  • Acute Fatty Liver of Pregnancy
  • HELLP Syndrome
  • Intrahepatic Cholestasis of Pregnancy

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology


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