@article{d4c4186758264314a89989af3b456f1b,
title = "Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles",
abstract = "A chip-based approach for electrochemical characterization and detection of microsomes and exosomes based on direct electro-oxidation of metal nanoparticles (MNPs) that specifically recognize surface markers of these vesicles is reported. It is found that exosomes and microsomes derived from prostate cancer cells can be identified by their surface proteins EpCAM and PSMA, suggesting the potential of exosomes and microsomes for use as diagnostic biomarkers.",
keywords = "electrochemistry, exosomes, microsomes, nanoparticles, prostate cancer",
author = "Zhou, {Yi Ge} and Mohamadi, {Reza M.} and Mahla Poudineh and Leyla Kermanshah and Sharif Ahmed and Safaei, {Tina Saberi} and Jessica Stojcic and Nam, {Robert K.} and Sargent, {Edward H.} and Kelley, {Shana O.}",
note = "Funding Information: The authors acknowledge the Canadian Institute for Health Research for their generous support of this work through an Emerging Team Grant, the Ontario Research Fund for a Research Excellence Grant, the Canadian Cancer Society Research Institute for an Innovation Grant, and the Natural Sciences and Engineering Council of Canada. The authors thank the ECTI facility at University of Toronto for their cleanroom facilities. Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2016",
month = feb,
day = "10",
doi = "10.1002/smll.201502365",
language = "English (US)",
volume = "12",
pages = "727--732",
journal = "Small",
issn = "1613-6810",
publisher = "Wiley-VCH Verlag",
number = "6",
}
