Interstage weight gain for patients with hypoplastic left heart syndrome undergoing the hybrid procedure

Holly Miller-Tate, Jamie Stewart, Robin Allen, Nazia Husain, Kerry Rosen, John P. Cheatham, Mark Galantowicz, Clifford L. Cua*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Background: Weight gain during the interstage (IS) period for hypoplastic left heart (HLHS) patients has been associated with improved outcomes. IS home monitoring has been shown to improve mortality. No data exist on IS weight gain and home monitoring effects on weight gain for HLHS patients undergoing the hybrid procedure. Objective: Goal of this study was to describe the weight gain of patients with HLHS undergoing the hybrid procedure during the IS period, to determine if weight parameters were associated with mortality, and to determine if home monitoring improved weight gain. Methods: Retrospective review was performed. Patients were included if they had the diagnosis of HLHS and underwent hybrid procedure. Baseline demographics, surgical dates, and all IS weights were recorded. Results: Forty-four patients met inclusion criteria, 24 patients had IS monitoring. Time period evaluated was from April 2006 to June 2011. Mean birth weight of the total population was 3.13±0.61kg, age at hybrid was 5.84±4.10 days, weight z-score at hybrid discharge was -1.66±1.01, age at pre-Stage II was 6.12±1.37 months, IS weight gain was 16.85±5.94g/day, and weight z-score pre-Stage II was -2.25±1.28. Monitored patients had significantly higher weight z-score pre-Stage II (-1.67±0.98 vs. -2.82±1.28) and lower change in weight z-score (-0.26±0.97 vs. -1.24±1.06). Eight patients died IS. There was a significant difference in weight gain per day in those that survived the IS period (17.87±4.75g/day vs. 12.28±8.65g/day). There were no significant differences in weight characteristics in patients that survived the Stage II procedure (n=28) vs. those that did not (n=7). Conclusion: Home monitoring improved IS weight gain in patients undergoing the hybrid procedure. Decreased weight gain per day was associated with IS mortality.

Original languageEnglish (US)
Pages (from-to)228-233
Number of pages6
JournalCongenital Heart Disease
Issue number3
StatePublished - May 1 2013


  • Home Monitoring
  • Hypoplastic Left Heart Syndrome
  • Interstage
  • Weight Gain

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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